Haut (dermal)

European Commission — CosIng: In the EU, titanium dioxide is listed for cosmetic use as a colorant and UV filter, with restrictions on inhalable powder and aerosol forms under Regulation (EC) 1223/2009. WHO / IARC: IARC classified titanium dioxide as possibly carcinogenic to humans (Group 2B) on the basis of inhalation of the powder — a hazard classification, not an exposure-specific verdict for finished creams.

EU SCCS / European Commission: In the EU, BHA is flagged by the SCCS in opinion SCCS/1682/25 (adopted 26 March 2026) reviewing potential endocrine activity in dermal cosmetic use at in-use concentrations.

European Commission: The EU restricted phenoxyethanol as a cosmetic preservative to a maximum of 1.0% under Regulation (EC) 1223/2009, Annex V. France ANSES / ANSM: France's authority flagged by recommendation that phenoxyethanol not be used in leave-on products intended for the nappy area of children aged three and under.

European Commission: The EU restricted propylparaben and butylparaben to a combined maximum of 0.14% (Regulation (EU) 358/2014) and prohibited five longer-chain parabens (Regulation (EU) 1004/2014). EU SCCS: The EU SCCS flagged by review certain parabens for potential endocrine activity, which informed the EU concentration limits; longer-chain parabens carried the greatest uncertainty.

European Commission: The EU restricted cosmetic retinol and retinyl esters to 0.05% retinol-equivalent in body lotion and 0.3% in other leave-on and rinse-off products under Regulation (EU) 2024/996. EU SCCS: Above the new EU leave-on caps and with prolonged daily use across several products, topical vitamin A may contribute to a consumer's total systemic vitamin A intake, per the SCCS assessment.

US FDA: A product contains glycerin as a widely used humectant; the US lists it as a permitted multi-purpose ingredient under 21 CFR 182.1320.

European Union / EUR-Lex: The EU restricted by Regulation (EU) 2023/1545 fragrance-allergen labelling in cosmetic products, adding individual disclosure requirements above set thresholds. European Union / EUR-Lex: The EU flagged by Regulation (EU) 2023/1545 additional fragrance allergens for individual labelling in cosmetic products above set thresholds.

European Union / EUR-Lex: The EU restricted by Regulation (EU) 2022/1181 finished cosmetic products that release formaldehyde to carry the warning "releases formaldehyde" above 0.001% released formaldehyde. European Union / EUR-Lex: The EU flagged by Regulation (EU) 2022/1181 finished products containing formaldehyde releasers for the warning "releases formaldehyde" above 0.001% released formaldehyde.

European Union / EUR-Lex: The EU restricted by Regulation (EU) 2022/1176 benzophenone-3 uses in cosmetic UV-filter applications through Annex VI changes. European Union / EUR-Lex: The EU flagged by Regulation (EU) 2022/1176 benzophenone-3 in the cosmetic UV-filter amendment package.

US Federal Register / FDA: The US restricted by the 2016 FDA final rule triclosan in OTC consumer antiseptic wash products. US Federal Register / FDA: FDA restricted by final rule triclosan for OTC consumer antiseptic wash products; this scope does not cover every cosmetic product type.

IARC Monographs: IARC classified by Monographs talc as probably carcinogenic to humans (Group 2A); this is a hazard classification, not a product-specific exposure estimate. US FDA: FDA flagged by cosmetic ingredient page talc as an ingredient used in cosmetics and tracks the cosmetic talc issue separately from food uses.

European Union / EUR-Lex: The EU restricted by Regulation (EU) 2016/1198 methylisothiazolinone use in cosmetics, removing leave-on uses from the permitted preservative scope. European Union / EUR-Lex: The EU restricted by Regulation (EU) 2016/1198 methylisothiazolinone in cosmetics by separating permitted rinse-off use from leave-on products.